ADVANT 16MG TAB
ADVANT 16MG TABLET:
Advant 16mg tablet is a pro-drug that is hydrolyzed to Candesartan when absorbed through gastrointestinal tract. Advant 16mg tablet is selective AT1 subtype angiotensin 2 receptor antagonist.
Advant 16mg tablet is used to treat hypertension in adults and children 1to < 17 years of age. In treatment of hypertension, Advant 16mg tablet can be used alone or in combination with other hypertensive drugs.
Advant 16mg is indicated for the treatment of heart failure in patients with left ventricular systolic dysfunction.
The most common adverse effects of Advant 16mg are headache and dizziness. Other important side effects include: Paresthesia, Dyspepsia, Tachycardia, Hyperuricemia, Myalgia, Depression, etc.
Advant 16mg tablet like other hypertensive agents may cause excessive decrease in blood pressure in patients with ischemic cardiopathy that can result in myocardial infarction or stroke.
WHEN NOT TO USE:
Advant 16mg tablets are not used in patients who are hypersensitive to this drug or any ingredient of Advant 16mg tablets.
- Concurrent use of Advant 16mg tablets and NSAID’s may lead to the higher risk of increasing renal functions.
- Careful monitoring of lithium levels should be done when Advant 16mg is co-administered with lithium.
In adults, the usual recommended starting dose of Advant 16mg is 16mg once daily if Advant 16mg is used as a monotherapy. The total daily dose of Advant 16mg ranges from 16mg-32mg.
In pediatrics, Advant 16mg can be administered either once daily or divided into two equal doses.
- Children 1 to <6 years of age: 0.05-0.4 mg/kg/day. Recommended starting dose is 0.20mg/kg.
- Children 6 to <17 years of age: For children who are less than 50 kg, Advant 16mg dose is 2-16mg/day. For children who are greater than 50kg, Advant 16mg dose is 4-32mg/day.
Advant 16mg starting recommended dose for heart failure is 4mg once daily. If tolerated by patients, the dose can be doubled at approximately 2 weeks interval to achieve the target of 32mg once daily.
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- Consult your doctor or pharmacist if you have an underlying medical condition, are taking any other medication or complementary therapy, or if symptoms persist.
- Please read the enclosed instruction leaflet.
- Keep out of reach of children.