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Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes heart attacks and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure liver disease) by removing excess fluid and improving symptoms such as breathing problems.

This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone).

Spironolactone is known as a "water pill" (potassium-sparing diuretic).

Side Effects:

Drowsiness dizziness lightheadedness stomach upset diarrhea nausea vomiting or headache may occur. To minimize lightheadedness get up slowly when rising from a seated or lying position. If any of these effects persist or worsen notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects including: increased thirst signs of kidney problems (such as change in the amount of urine) mental/mood changes unusual fatigue/weakness muscle spasms menstrual period changes breast pain breast enlargement (gynecomastia) in men sexual function problems signs of infection (e.g. fever persistent sore throat) severe stomach/abdominal pain persistent nausea/vomiting vomit that looks like coffee grounds dark urine yellowing of the eyes/skin easy bruising/bleeding.

This medication may lead to high levels of potassium especially in patients with kidney problems. If not treated very high potassium levels can be fatal. Tell your doctor right away if you notice any of the following serious side effects: slow/irregular heartbeat muscle weakness.

A very serious allergic reaction to this drug is rare. However get medical help right away if you notice any symptoms of a serious allergic reaction including: rash itching/swelling (especially of the face/tongue/throat) severe dizziness trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above contact your doctor or pharmacist.


Before taking spironolactone tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication tell your doctor or pharmacist your medical history especially of: kidney problems liver problems untreated mineral imbalance (such as high potassium low sodium) decreased adrenal gland function (Addisons disease).

Before having surgery tell your doctor or dentist about all the products you use (including prescription drugs nonprescription drugs and herbal products).

This medication may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium consult your doctor or pharmacist. Limit foods high in potassium such as bananas tomatoes potatoes and low-salt milk. Consult your doctor or pharmacist for more details including recommendations.

This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive use machinery or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Older adults may be more sensitive to the side effects of this drug especially the effects on potassium (see Side Effects section).

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Belongs to the category: Heart failure & edema, Heart health