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CO-TASMI 80MG+12.5MG TAB

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Original price Rs.280.00
Current price Rs.260.40

CO-TASMI 80MG+12.5MG TABLET

CO TASMI 80mg+12.5mg tablet is a combination of telmisartan, an orally active angiotensin II antagonist, and hydrochlorothiazide, a diuretic.

USES:

CO TASMI 80mg+12.5mg tablet is indicated for the treatment of hypertension. This fixed dose combination is not indicated for initial therapy.

SIDE EFFECTS:

CO TASMI 80mg+12.5mg tablet may cause:

  • Common: Dizziness
  • Uncommon: Hypokalemia, anxiety, syncope, paresthesia, vertigo, tachycardia, arrhythmias, hypotension, or thostatic hypotension, dyspnea, diarrhea, dry mouth, flatulence, back pain, muscle spasms, myalgia, erectile dysfunction, chest pain and blood uric acid increase.

PRECAUTIONS:

  • As with any antihypertensive agent, excessive reduction of blood pressure in patients with ischemic cardiopathy or ischemic cardiovascular disease could result in a myocardial infarction or stroke. –
  • Hypersensitivity reactions to hydrochlorothiazide may occur in patients with or without a history of hypersensitivity or bronchial asthma, but are more likely in patients with such a history.
  • Exacerbation or activation of systemic lupus erythematous has been reported with the use of thiazide diuretics.
  • When driving vehicles or operating machinery it must be borne in mind that dizziness or drowsiness may occasionally occur when taking antihypertensive therapy.
  • Cases of photosensitivity reactions have been reported with thiazide diuretics.

WHEN NOT TO USE:

  • In patients who are hypersensitive to this drug or any component of this product.
  • In patients with anuria or hypersensitivity to other sulfonamide-derived drugs, due to hydrochlorothiazide component in the preparation.
  • Refractory hypokalemia and hypercalcemia.
  • During second and third trimesters of pregnancy and lactation. − With cholestasis and biliary obstructive disorders.
  • With severe hepatic impairment.
  • With severe renal impairment.

INTERACTIONS:

  • Lithium: Coadministration of lithium and telmisartan + hydrochlorothiazide is not recommended. If this combination proves essential, careful monitoring of serum lithium level is recommended during concomitant use.
  • Digoxin: It is recommended that digoxin level be monitored when initiating, adjusting and discontinuing telmisartan to avoid over- or under-digitalization.
  • Medicinal products associated with potassium loss and hypokalemia (e.g., other kaliuretic diuretics, laxatives, corticosteroids, ACTH, amphotericin, carbenoxolone, penicillin G sodium, salicylic acid and derivatives).
  • Anti-diabetic medicinal products (oral agents and insulin): Dosage adjustment of the anti-diabetic medicinal products may be required.
  • Metformin: Metformin should be used with precaution as there could be a risk of lactic acidosis induced by a possible functional renal failure linked to hydrochlorothiazide.
  • Cholestyramine and colestipol resins: Absorption of hydrochlorothiazide is impaired in the presence of anionic exchange resins.

DOSE:

  • CO TASMI can be taken with or without meals.
  • CO TASMI may be administered with other anti-hypertensive agents.
  • Usually effective dose of telmisartan is 40mg once daily.

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  • Consult your doctor or pharmacist if you have an underlying medical condition, are taking any other medication or complementary therapy, or if symptoms persist.
  • Please read the enclosed instruction leaflet.
  • Keep out of reach of children.