FENOGET 200MG CAP
FENOGET 200MG CAPSULES:
Fenoget 200mg is a derivative of fibric acid and is a lipid lowering agent.
- Treatment of Hypercholesterolemia:
Fenoget is indicated as adjunctive therapy to diet for the reduction of LDL-C, Total-C, Triglycerides and Apo B in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb).
- Treatment of Hypertriglyceridemia
Fenoget is indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia).
The most common adverse reactions reported with Fenoget 200mg are:
Gastrointestinal (diarrhea, constipation, dyspepsia, flatulence), muscle pain, and skin reactions. There is a slightly increased risk of gallstones, inflamed liver (hepatitis), and muscle inflammation (myositis). Other adverse effects include: Headache, fatigue, muscle inflammation, inflammation of the pancreas (pancreatitis), balance problems involving the inner ear (vertigo), respiratory problems, muscle breakdown (rhabdomyolysis), hair loss (alopecia), alteration in results of liver function tests, sexual problems.
Periodic determination of serum lipids should be obtained to determine the lowest effective dose of fenofibrate. Therapy should be withdrawn in patients who do not have an adequate response after two months of treatment with the maximum recommended dose.
WHEN NOT TO USE:
- With hypersensitivity to fenofibrate or any of the formulation components.
- With severe renal dysfunction.
- With hepatic dysfunction, including primary biliary cirrhosis and unexplained persistent liver function abnormality.
- Pre-existing gall bladder disease.
- Fenofibrate should not be used in nursing mothers.
- Caution should be exercised when anticoagulants are given in conjunction with fenofibrate because of the potentiation of coumarin-type anticoagulants in prolonging the prothrombin time/INR.
- The combined use of fenofibrate and HMG-CoA reductase inhibitors should be avoided unless the benefit of further alterations in lipid levels is likely to outweigh the increased risk of this drug combination.
- Since bile acid sequestrants may bind other drugs given concurrently, patients should take fenofibrate at least 1 hour before or 4-6 hours after a bile acid binding resin to avoid impeding its absorption.
- Medications known to exacerbate hypertriglyceridemia (betablockers, thiazides, estrogens) should be discontinued or changed if possible prior to consideration of triglyceride-lowering drug therapy.
The initial dose of Fenoget 200mg capsules is 200mg per day
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- Consult your doctor or pharmacist if you have an underlying medical condition, are taking any other medication or complementary therapy, or if symptoms persist.
- Please read the enclosed instruction leaflet.
- Keep out of reach of children.