LYTA 30MG CAP
LYTA 30MG CAPSULE:
Lyta is Duloxetine which is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI).
Lyta 30mg capsule is indicated for:
- The treatment of major depressive disorder (MDD).
- The management of neuropathic pain (DPNP) associated with diabetic peripheral neuropathy.
- The treatment of generalized anxiety disorder. The management of fibromyalgia.
- The treatment of moderate to severe stress urinary incontinence in women.
Lyta 30mg capsule has side effects including Nausea, headache, insomnia, fatigue, somnolence, dry mouth, dizziness, and constipation.
Suicidal thoughts and suicidal behaviours can occur during duloxetine therapy or early after treatment discontinuation. Close supervision of patients, and in particular those at high risk, should accompany drug therapy especially in early treatment and following dose changes. Patients (and caregivers of patients) should be alerted about the need to monitor for any clinical worsening, suicidal behaviour or thoughts, and unusual changes in behaviour, and to seek medical advice immediately if these symptoms present.
WHEN NOT TO USE:
Lyta 30mg capsules are contraindicated in patients:
- Taking monoamine oxidase inhibitors (MAOIs), due to the risk of serious, sometimes fatal, drug interactions with serotonergic drugs.
- With hypersensitivity to the active substance or to any of the excipients.
- Taking with fluvoxamine, ciprofloxacin or enoxacine (i.e., potent CYP1A2 inhibitors).
- With uncontrolled hypertension that could expose patients to a potential risk of hypertensive crisis.
- With severe renal insufficiency with creatinine clearance (CLcr) < 30mL/min.
- With liver disease resulting in hepatic insufficiency
Lyta 30mg capsule is contraindicated with the following:
- Serotoninergic agents
Usual initial doses of 20mg or 30mg twice daily, or 60mg once daily.
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