NEBIX 5MG TAB
WHAT IS NEBIX 5MG?
Nebivolol belongs to the group of medicines known as Beta Blockers. It works on the heart and blood vessels. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.
WHAT ARE THE USES OF NEBIX 5MG?
NEBIX is indicated for the treatment of hypertension & treatment of stable mild and moderate chronic heart failure.
WHAT ARE THE SIDE EFFECTS OF NEBIX 5MG?
Gastrointestinal System Disorders: abdominal pain
Metabolic and Nutritional Disorders: hypercholesterolemia
Nervous System Disorders: paraesthesia
- Bloating or swelling of the face, arms, hands, lower legs, or feet
- chest pain or discomfort
- difficult or labored breathing
- lightheadedness, dizziness, or fainting
- rapid weight gain
- shortness of breath
- slow or irregular heartbeat
- tightness in the chest
- tingling of the hands or feet
- unusual tiredness or weakness
- unusual weight gain or loss
WHEN NOT TO USE NEBIX 5MG?
Nebivolol is contraindicated in severe bradycardia, heart block greater than first degree, patients with cardiogenic shock, decompensated cardiac failure, sick sinus syndrome (unless a permanent pacemaker is in place), patients with severe hepatic impairment (Child-Pugh >B) and hypersensitive to any component of this product. NEBIX should not be used during pregnancy and in lactating mothers. Patients should consult with their physician before taking any medicine.
WHAT ARE THE PRECAUTIONS OF NEBIX 5MG?
- In general, patients with bronchospastic diseases should not receive β-blockers.
- Because beta-blocker withdrawal has been associated with an increased risk of MI and chest pain, patients already on beta-blockers should generally continue treatment throughout the perioperative period.
- Nonselective β-blockers may potentiate insulin-induced hypoglycemia and delay recovery of serum glucose levels.
- Abrupt withdrawal of β-blockers may be followed by an exacerbation of the symptoms of hyperthyroidism or may precipitate a thyroid storm.
- Renal clearance of Nebivolol is decreased in patients with severe renal impairment.
WHAT ARE THE INTERACTIONS NEBIX 5MG?
- Use caution when Nebivolol is co-administered with CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine, etc.)
- Do not use Nebivolol with other β-blockers. In patients who are receiving Nebivolol and clonidine, discontinue Nebivolol for several days before the gradual tapering of clonidine.
- Both digitalis glycosides and β-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can increase the risk of bradycardia.
- Nebivolol can exacerbate the effects of myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists or antiarrhythmic agents, such as disopyramide.
WHAT IS THE DOSE OF NEBIX 5MG?
The starting dose of NEBIX is 5mg once daily in most patients preferably at the same time of the day.
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