Skip to content

RANOLA TABLET 500MG

Save 5%
Original price Rs.159.67
Current price Rs.151.69

RANOLA TABLET 500MG

WHAT IS RANOLA TABLET 500MG?

Ranola belongs to Other Anti-anginal & Anti-ischaemic drugs which is Ranolazine used for the treatment of angina. Ranolazine has anti-ischemlc and antlanginal effects that do not depend upon reductions in heart rate or blood pressure. Ranolazine at therapeutic levels can inhibit the cardiac late sodium current (INa).

WHAT ARE THE USES OF RANOLA TABLET 500MG?

Ranolazine is indicated for the treatment of chronic angina. Ranolazine may be used with beta-blockers, nitrates, calcium channel blockers, anti-platelet therapy, lipid-lowering therapy, ACE inhibitors, and angiotensin receptor blockers. It has been shown to decrease angina episodes in patients with coronary artery disease on maximal doses of amlodipine. Because Ranolazine prolongs the QT interval, it should be reserved for patients who have not achieved an adequate response with other antianginal drugs.

 

RANOLA TABLET 500MG USES IN URDU

Ranolazine کو دائمی انجائنا کے علاج کے لیے تجویز کیا جاتا ہے۔ Ranolazine کو بیٹا بلاکرز، نائٹریٹس، کیلشیم چینل بلاکرز، اینٹی پلیٹلیٹ تھراپی، لپڈ کم کرنے والی تھراپی، ACE روکنے والے، اور انجیوٹینسن ریسیپٹر بلاکرز کے ساتھ استعمال کیا جا سکتا ہے۔ یہ املوڈپائن کی زیادہ سے زیادہ خوراکوں پر کورونری دمنی کی بیماری والے مریضوں میں انجائنا کی اقساط کو کم کرتا دکھایا گیا ہے۔ چونکہ Ranolazine QT وقفہ کو طول دیتا ہے، اس لیے اسے ان مریضوں کے لیے مخصوص کیا جانا چاہیے جنہوں نے دوسری اینٹی اینجینل دوائیوں کے ساتھ مناسب ردعمل حاصل نہیں کیا ہے

WHAT ARE THE SIDE EFFECTS OF RANOLA 500MG TABLET?

Cardiac Disorders: bradycardia, palpitations
Ear and Labyrinth Disorders: tinnitus, vertigo
Gastrointestinal Disorders: abdominal pain, dry mouth, vomiting
General Disorders and Administrative Site Adverse Events: peripheral edema
Respiratory, Thoracic, and Mediastinal Disorders: dyspnea
Vascular Disorders: hypotension, orthostatic hypotension

WHEN NOT TO USE RANOLA 500MG TABLET?

Ranolazine is contraindicated in patients:

  • With pre-existing QT prolongation
  • With hepatic impairment
  • Taking QT prolonging drugs
  • Taking potent and moderately potent CYP3A inhibitors such as ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, and saquinavir, including diltiazem.

 

 

WHAT ARE THE PRECAUTIONS OF RANOLA 500MG TABLET?

  • Ranolazine blocks QTc and prolongs the QTc interval in a dose-related manner. Clinical experience in an acute coronary syndrome population did not show an increased risk of proarrhythmia or sudden death.

    Co-administration of ranolazine with digoxin increases the plasma concentrations of digoxin by approximately 1.5-fold and the dose of digoxin may have to be reduced accordingly. The dose of other P-gp substrates may have to be reduced as well when ranolazine Is co-admlnistered. Caution should be exercised when co-adminlstering ranolazine with P-gp inhibitors such as ritonavir or cydosporine.

 

WHAT ARE THE INTERACTIONS RANOLA 500MG TABLET?

CYP 3A Inhibitors: Do not use Ranolazine with strong CYP 3A inhibitors. With moderate CYP 3A inhibitors (e.g., diltiazem, verapamil, erythromycin) limit maximum dose of ranolazine to 500 mg twice daily.

CYP 3A Inducers: Do not use Ranolazine with inducers.

P-gp Inhibitors (e.g., Cyclosporin): May need to lower the Ranolazine dose based on clinical dose.

Drugs transported by P-gp or metabolized by CYP2D6 (eg., digoxin, TCA): May need reduced doses of these drugs when used with ranolazine.

 

WHAT IS THE DOSE OF RANOLA 500MG TABLET?

Initiate Ranolazine dosing at 500 mg twice daily and increase to 1000 mg twice daily, if needed, based on clinical symptoms. Take Ranolazine with or without meals. The maximum recommended daily dose of Ranolazine is 1000 mg twice daily.

 

Disclaimer

Consult your doctor and discuss your queries related to any medicine or disease. EHAD PHARMACY aim is to make sure that its consumers get material that is correct, reviewed by an expert and error-free. However, the material stated here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions.

 

Buy medicine online in Pakistan from most trusted online pharmacy EHAD. Free delivery along with cash on delivery & up to 35% discount. Buy from EHAD Online Pharmacy, your medicine, mother care, baby care, personal care, healthcare supplements and wellness products online. Give us a call to order medicine at +92 334 1113423.

 

Belongs to the category: Angina, Heart health