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Treviamet 50mg+1000mg tablet contains two oral antihyperglycemic agents with complementary mechanism of action to improve glycemic control with type 2 diabetes.


Treviamet 50mg+1000mg tablet is used as an anti-diabetic agent.

  • Dual Therapy In combination with metformin HCl or with a sulphonylurea or with a PPARγ agonist (i.e., thiazolidinedione’s) when the treatment with the single agent alone with diet and exercise does not provide adequate glycemic control.
  • Triple Therapy In combination with metformin HCl and a sulphonylurea or with metformin HCl and a PPARγ (i.e., thiazolidinedione’s) when dual therapy with these agents, with diet and exercise, does not provide adequate glycemic control.
  • Combination with Insulin.


Treviamet 50mg+1000mg گولی ایک اینٹی ذیابیطس ایجنٹ کے طور پر استعمال ہوتی ہے۔

  • دوہری تھراپی میٹفارمین ایچ سی ایل کے ساتھ یا سلفونی لوریہ کے ساتھ یا پی پی اے آرγ ایگونسٹ (یعنی تھیازولیڈینیڈینز) کے ساتھ جب خوراک اور ورزش کے ساتھ واحد ایجنٹ کے ساتھ علاج مناسب گلیسیمک کنٹرول فراہم نہیں کرتا ہے۔

ٹرپل تھراپی میٹفارمین ایچ سی ایل اور سلفونی لوریہ کے ساتھ یا میٹفارمین ایچ سی ایل اور پی پی اے آرγ (یعنی تھیازولیڈینیڈینز) کے ساتھ جب ان ایجنٹوں کے ساتھ دوہری تھراپی، خوراک اور ورزش کے ساتھ، مناسب گلیسیمک کنٹرول فراہم نہیں کرتی ہے۔

  • انسولین کے ساتھ ملاپ۔




Treviamet 50mg+1000mg tablet may cause nausea, somnolence, diarrhea, upper abdominal pain and blood glucose decreased.


Treviamet 50mg+1000mg tablet is contraindicated in:

  • Patients with type 1 diabetes.
  • Renal disease or renal dysfunction, e.g., as suggested by serum creatinine levels ≥ 1.5mg/dL (males) ≥ 1.4mg/dL (femal es), or a bnormal creatinine clearance, which may also result from conditions such as cardiovascular collapse (shock), acute myocardial infarction, and septicemia.
  • Patients with known hypersensitivity to Sitagliptin, Metformin HCl or any other component of the product.
  • Acute or chronic metabolic acidosis including ketoacidosis, with or without coma.
  • Children below 18 years of age.


  • Since impaired hepatic function has been associated with some cases of lactic acidosis, Treviamet 50mg+1000mg tablet should generally be avoided in patients with clinical or laboratory evidence of hepatic disease.
  • After initiation of Sitagliptin, patients should be observed carefully for signs and symptoms of pancreatitis. If pancreatitis is suspected, Sitagliptin should promptly be discontinued and appropriate management should be initiated.


Treviamet 50mg+1000mg tablet have following interactions:

  • Sitagliptin has a small effect on plasma digoxin concentrations. No dosage adjustment of digoxin is recommended. However, patients at risk of digoxin toxicity should be monitored forthiswhen Sitagliptin and digoxin are administered concomitantly.
  • Furosemide increased the Metformin HCl plasma and blood Cmax by 22% and blood AUC by 15%, without any significant change in Metformin HCl renal clearance.
  • Co-administration of nifedipine increased plasma Metformin HCl Cmax and AUC by 20% and 9%, respectively.


The daily recommended dose of Treviamet 50mg+1000mg tablet is 100mg.


Consult your doctor and discuss your queries related to any medicine or disease. EHAD PHARMACY's aim is to make sure that its consumers get material that is correct, reviewed by an expert, and error-free. However, the material stated here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications, or drug interactions.

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Belongs to the category: Diabetes medicines, Type 2